Paradoxical upgrading reaction in extra-pulmonary tuberculosis: association with vitamin D therapy

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Paradoxical upgrading reaction in extra-pulmonary tuberculosis: association with vitamin D therapy

SETTING Glasgow, Scotland, UK. BACKGROUND Paradoxical reactions in tuberculosis (TB) are a notable example of our incomplete understanding of host-pathogen interactions during anti-tuberculosis treatment. OBJECTIVES To determine risk factors for a TB paradoxical reaction, and specifically to assess for an independent association with vitamin D use. DESIGN Consecutive human immunodeficienc...

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Tuberculosis paradoxical reaction.

T is endemic in this part of the world. We frequently encounter patients with both pulmonary and extrapulmonary tuberculosis regardless of whether they are infected with human immunodeficiency virus (HIV) or not. It is not uncommon for physicians to see clinical or radiological, or both, worsening of the disease while their patient is on anti-tuberculous treatment, the so-called paradoxical rea...

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Association of Serum Vitamin D Levels with Bacterial Load in Pulmonary Tuberculosis Patients

BACKGROUND Vitamin D is known to have diverse effects on various systems in the body. There is evidence to suggest that a link exists between the serum vitamin D status and tuberculosis. The present study was designed to assess the alterations in serum 25-hydroxyvitamin D levels in newly diagnosed sputum acid fast bacilli (AFB) positive pulmonary tuberculosis patients and to study the associati...

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The effect of vitamin D as adjuvant therapy in pulmonary tuberculosis with moderate-advance lesion.

Tuberculosis is a major health problem, with a prediction by the World health organization in 1995 that every year there would be approximately 9 million new cases world-wide. In developing countries, 25% of all deaths is caused by this disease – a cause of death that can be prevented or at least minimized. Ninety-five percent of all TB cases are found in developing countries, in which 755 fall...

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ژورنال

عنوان ژورنال: The International Journal of Tuberculosis and Lung Disease

سال: 2017

ISSN: 1027-3719

DOI: 10.5588/ijtld.16.0927